Hypothesis Volume 3, Issue 11 pp 1051—1062

Hormesis does not make sense except in the light of TOR-driven aging


Figure 1. Paradoxical links between damage and aging. (A) If agings is caused by damage, then hormetic damage should accelerate aging. Also food by providing resources should becelerate aging. Both prediction contradict observations, making the model incorrect. (B) Paradoxical model assumes that (a) damage decrease damage and (b) the less resources (food), the more resources can be used for anti-aging repair. These assumptions are paradoxical but nevertheless are needed to fit predictions and observations. Paradoxical links are shown in red.