Review Volume 4, Issue 12 pp 878—886

Embryonic stem cells and inducible pluripotent stem cells: two faces of the same coin?


Figure 3. Human cell-based therapy. Bone marrow transplantation is widely employed in the clinic for several diseases including cancer and haematological disorders. More recently, MSCs are stepping in. They could be used to treat inflammatory conditions such as Multiple Sclerosis and Pulmonary Fibrosis. The employment of iPSCs in cell-based therapy is a relative new tool. However, because their potential tumorigenicity in the clinical setting remains to be clarified, perhaps iPSCs should stay on the bench meanwhile and be used in drug screening and human disease models.