Research Paper Volume 8, Issue 9 pp 2023—2038

Increased expression of long-noncoding RNA ZFAS1 is associated with epithelial-mesenchymal transition of gastric cancer

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Figure 2. Relative expression level of lncRNA ZFAS1 in 77 paired GC plasmas and 60 healthy controls. (A) ZFAS1 was highly expressed in GC patients compared to healthy controls (P < 0.0001) and patients after surgical treatment (P < 0.0001). (B-D) ZFAS1 was highly expressed in patients with high TNM stage (B), depth invasion (C), and distant metastasis (D). The relative expression level was calculated using 2-ΔCT method. **, P < 0.01, *, P < 0.05. Statistical analyses were conducted by Wilcoxon test (A) and Mann-Whitney U test (B, C, D and E).