Research Paper Volume 8, Issue 9 pp 2232—2252

Global gene profiling of aging lungs in Atp8b1 mutant mice

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Figure 5. Ingenuity Pathway Analysis reveals dysregulated Calcium signaling in aged Atp8b1 mutant mice. The transcripts Atp2b1 and Atp2b2 encoding ATP2B1 and ATP2B2 that play an important role in calcium signaling were decreased in Atp8b1 mutant lung in age-dependent manner.