Research Paper Volume 8, Issue 11 pp 2611—2634

Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction

Figure 3. Excess fatty acids in aging decreases arachidonic acid (AA) metabololipidome post-MI. (A) Hierarchal cluster analysis of change in AA metabolites due to young and aging with and without SO diet. Color code bar representing change in expression from green (-1 lowest decrease) to red (+1 highest increase). (B) Venn diagram representing the number of AA metabolites affected due to age (young and aging) and SO-diet post-MI. (C) PCA analysis of AA metabolites of post-MI with respect to age and diet. (D) Bar graph representing change in AA metabolite production at pre-MI (No-MI controls) and d1 post-MI.