Research Paper Volume 8, Issue 11 pp 2611—2634

Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction

Figure 6. Post-MI impact of fatty acids during aging on cardiorenal-axis. (A) Immunofluorescence images representing TUNEL positive cells (green) in young and aging-SO fed mice. Nuclei are stained with propidium iodide (Red). (B) PAS staining indicates granulomatous kidney inflammation. (C) Pre- and post-MI plasma creatinine level and mRNA expression of TNF-α and IL-1β, in kidney. (D) Pre- and post-MI mRNA and protein expression of NGAL in kidney. *p<0.05 vs young-LC; $p<0.05 LC vs SO. Values are means ±SEM; n=; n=2 at d0, n=3-4 at d1/group.