Research Paper Volume 8, Issue 11 pp 2827—2847

Tethering telomerase to telomeres increases genome instability and promotes chronological aging in yeast


Figure 5. CLS assay of cells with overlong telomeres but no CDC13-EST2 fusion gene (A) CLS of normal- and overlong-telomere cells after plasmids eviction (21st streakout) (B) Southern blot analysis of telomere length using telomeric TG1-3 probe. (C) CLS of wild-type (4th streakout) and rif1∆ (4th streakout). (D) Telomere length detection by Southern blot at CLS D1 and D15.