Research Paper Volume 9, Issue 4 pp 1130—1142

Telomeres and the natural lifespan limit in humans

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Figure 4. Predicted proportion of the composite study population reaching the telomere brink (TB; 5 kb) based on period life table mortality (period), life expectancy of 100 years (LE-100), LTL ranking and LTL attrition. Individuals were ranked by quintiles, where the shortest (1st) LTL quintile is 0-19% and the longest (5th) LTL quintile is 80-99%. The panels display findings for four age groups: 35 years (range 30-40 years); 50 years (range 45-55 years); 60 years (range 55-65 years); 80 years (range 75-85 years), based on different LTL attrition rates (15-45 bp/year).