Research Paper Volume 10, Issue 2 pp 212—228

Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating DNMT1 via ZEB1

Figure 6. DNMT1 and ZEB1 expression is reduced in sun-exposed human skin. (A)Representative immunohistochemical staining images of matched human sun-exposed or non-sun-exposed skin specimens from within the same individual. Sections were imaged using primary antibodies raised against DNMT1 or ZEB1 (C, D) (Magnification= 400×). (B) Bar graph shows quantitative analysis of scanning density values of these proteins, * vs non-sun exposed, P < 0.05.