Research Paper Volume 10, Issue 4 pp 632—644

KCNQ1OT1 promotes melanoma growth and metastasis

Figure 2. KCNQ1OT1 is a target of miR-153. (A) Correlation between miR-153 expression and KCNQ1OT1. (B) Prediction that KCNQ1OT1 can specifically bind to the miR-153 by LNCBASE. (C, D) Fluorescence intensity was measured in HACAT cells co transfected with miR-153 or miR-153 AS and KCNQ1OT1 WT/MUT construct. A GFP vector was used as a control. (E) Relative RNA of KCNQ1OT1 was measured in HACAT cells transfected with miR-153 or miR-153 AS. (F) Relative RNA of miR-153 was measured in HACAT cells transfected with KCNQ1OT1 WT, KCNQ1OT1 MUT or si-KCNQ1OT1.