Research Paper Volume 10, Issue 4 pp 689—700

Association of VAMP5 and MCC genetic polymorphisms with increased risk of Hirschsprung disease susceptibility in Southern Chinese children

Figure 1. The linkage disequilibrium patterns (LD) of the SNPs in VAMP5 included in this study. Haplotype blocks in VAMP5 were defined according to the LD value in Guangzhou replication. The numbers in the boxes are the pairwise correlation coefficient r2 between respective SNPs. Darker shades of gray indicate higher value of LD. Lighter shades of gray represents lower value of LD. The highest LD value of 0.58 was observed between rs10206961 and rs1254900, while rs14242 showed limited LD with all the other SNPs among these populations.