Research Paper Volume 10, Issue 5 pp 1027—1052

Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice

Figure 3. Heat map of significantly differentially expressed genes in liver, skeletal muscle, brain and WAT from either KOAL or WTDR mice compared to WTAL. A total of 1172 genes were significantly differentially expressed. Red represents up-regulated genes and blue represents down-regulated genes.