Research Paper Volume 10, Issue 5 pp 1027—1052

Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice

Figure 5. Shared and distinct gene expression profile between KOAL, KODR and WTDR mice. Venn diagram of similar and separate expressed genes across (a) liver, (b) skeletal muscle, (c) WAT and (d) skeletal muscle. Significantly up-regulated genes are shown in red and significantly down-regulated genes are shown in blue. Common genes that are significantly up- or down-regulated are found in overlapping circles. The numbers in the bottom far right denotes the number of genes expressed but not significantly up-regulated (red) or down-regulated (blue).