Research Paper Volume 10, Issue 6 pp 1281—1293

CircSNCA downregulation by pramipexole treatment mediates cell apoptosis and autophagy in Parkinson’s disease by targeting miR-7

Figure 1. Genes related to the mechanism of PPX treatment of PD. (A) Number of genes that are concerned solely with PD or AD and with both diseases selected from DiGSeE. (B) 16 genes were related to both PD and AD. (C) SNCA was directly downregulated by PPX according to STITCH. (D) The protein-protein interactions (PPI) of apoptotic-related genes with SNCA.