Research Paper Volume 10, Issue 7 pp 1597—1608

Aging exacerbates mortality of Acinetobacter baumannii pneumonia and reduces the efficacies of antibiotics and vaccine

Figure 4. Elevated numbers of inflammatory cells after A.baumannii infection in aged mice. Young and aged mice were infected intratracheally with 5×106 CFU LAC-4 and BALF were collected at 0 h and 24 hpi. Number of total cells (A), monocytes (B), macrophages (C), and neutrophils (D) in BALF of young and aged mice were determined. Data are presented as mean ± SEM of five mice per condition and represent one of 2 independent experiments. Statistical analyses were performed by Student’s t test. **, P < 0.01.