Research Paper Volume 10, Issue 7 pp 1666—1681

Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2

Figure 3. H2S donor treatments affect splicing factor transcript expression. The change in splicing factor mRNA levels in response to 24hr treatment with H2S donors are given ; Na-GYY4137 at 100 µg/ml, AP39, AP123, RT01 at 10 ng/ml. Green indicates up-regulated genes, red denotes down-regulated genes. The colour scale refers to fold-change in expression. Only statistically significant changes are presented in the heat map.