Research Paper Volume 10, Issue 7 pp 1682—1697

Global quantitative TPA-based proteomics of mouse brain structures reveals significant alterations in expression of proteins involved in neuronal plasticity during aging

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Figure 2. The effect of aging on total protein expression in brain structures. The comparison of proteins identified quantitatively in cortex, cerebellum and hippocampus and the number of proteins affected significantly (p<0.05) by aging (A).The total molar (pmol/mg) concentration of proteins in brain formations of young and middle-aged mice (B). Asterisks indicate a statistically significant difference (p < 0.05).