Figure 11. Metabolic effects of voluntary running in middle-age female mice. (A) Glucose tolerance test after 5-weeks running initiated at 10 months of age. n=11 for Running, n=7 for Sedentary mice. (B) Body composition. (C) Body and tissue weight at sacrifice after 7-week running. n=12 for Running, n=8 for Sedentary mice. (D) Western blotting of livers. (E) Quantification of western blotting. n=6 per group. * P<0.05, ** P<0.01, *** P<0.001. Values are means ± SEM.