**Figure 6.** **EE improves motor behavior and reduces anxiety.** (**A**, **B**) Rotarod treadmill test at the age of 19 months after 9-month EE (n=9 per group). Time remaining on rod (**A**), Speed at fall (**B**). (**C**-**E**) Open field test at the age of 12 months after 2-month EE (n=10 per group). Time spent at the center of arena (**C**), ratio of distance travelled in center to total distance (**D**), total distance travelled (**E**). (**F**, **G**) Novelty suppressed feeding test at the age of 20 months after 10-month EE (n=10 SE, n=9 EE). Latency to consumption (**F**), food consumption in standard cage after the test (**G**). (H) Cold induced defecation test at the age of 19.5 months after 9.5-month EE (n=10 SE, n=9 EE). (**I**, **J**) Forced swim test at the age of 20.5 months after 10.5-month EE (n=8 per group). Immobility in each min (**I**), total immobility time (**J**). * *P*<0.05, ** *P*<0.01. Values are means ± SEM.