Research Paper Volume 10, Issue 10 pp 2723—2740

Long-term intake of Lactobacillus paracasei KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice

Figure 3. The levels of proinflammatory cytokines in the serum were mitigated in aged mice fed a diet containing Lactobacillus paracasei KW3110 as compared with age-matched control mice. Serum was collected and subjected to multiplex analyses to determine levels of cytokines (IL-1β, IL-6, IL-13, IL-17, IFN-γ, TNF-α, KC, and MCP1) in young (3-months-old) and aged mice (22-months-old). Values are presented as the means ± SEM. Significance was assumed if the p value was < 0.05. *p < 0.05; **p < 0.01. CTL = control diet; KW3110 = Lactobacillus paracasei KW3110 diet; IL = interleukin; IFN = interferon; TNF = tumor necrosis factor; KC = keratinocyte chemoattractant; MCP1 = monocyte chemoattractant protein 1.