Research Paper Volume 10, Issue 10 pp 2723—2740

Long-term intake of Lactobacillus paracasei KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice

Figure 4. Intake of Lactobacillus paracasei KW3110 mitigated retinal inflammation. Intake of L. paracasei KW3110 in aged mice (17-months-old) suppressed the expression of inflammatory cytokines in retinal macrophage of aged mice. F4/80 and CD11b-positive macrophage in retina were gated as shown in (A), and median fluorescent intensity of intracellular IL-6, IFN-γ, and TNF-α were analyzed by flow cytometry (B-D). Significance was assumed if the p value was < 0.05; *p<0.05. All abbreviations are defined in the Figure 3 legend.