Research Paper Volume 10, Issue 11 pp 3104—3116

Inactivation of glycogen synthase kinase-3α is required for mitochondria-mediated apoptotic germ cell phagocytosis in Sertoli cells

Figure 3. GSK3α inhibition is required for apoptotic GCs clearance. (A) Apoptotic cells revealed by TUNEL assay on testis sections. Representative seminiferous tubules are shown. The green signal (arrow) indicates a TUNEL-positive nucleus. Con: control; HS: heat shock; SB: SB216763. Scale bar=20 μm. (B) Histogram showing the average number of TUNEL-positive cells per seminiferous tubule. Values are expressed as the mean ± SEM, n=15. Values with different superscripts are significantly different from each other (P<0.05).