Research Paper Volume 10, Issue 11 pp 3104—3116

Inactivation of glycogen synthase kinase-3α is required for mitochondria-mediated apoptotic germ cell phagocytosis in Sertoli cells

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Figure 3. GSK3α inhibition is required for apoptotic GCs clearance. (A) Apoptotic cells revealed by TUNEL assay on testis sections. Representative seminiferous tubules are shown. The green signal (arrow) indicates a TUNEL-positive nucleus. Con: control; HS: heat shock; SB: SB216763. Scale bar=20 μm. (B) Histogram showing the average number of TUNEL-positive cells per seminiferous tubule. Values are expressed as the mean ± SEM, n=15. Values with different superscripts are significantly different from each other (P<0.05).