Research Paper Volume 10, Issue 11 pp 3229—3248
Methanolic extract of Tamarix Gallica attenuates hyperhomocysteinemia induced AD-like pathology and cognitive impairments in rats
Figure 6. Treatment with TG mitigated Hcy-induced tau hyperphosphorylation. (A) Phosphorylation status of tau protein as measured by Western blotting in the hippocampus after Hcy treatment and TG supplementation. (B) Total tau (Tau5) normalized to β-actin. (C-E) Quantitative analysis of the blots of phosphorylated tau probed with several phosphorylated-tau antibodies normalized to total tau (Tau5). A significant decrease in tau hyperphosphorylation at several studied sites was seen following TG administration. The data were expressed as mean ± SEM (n = 6). ## P < 0.01, ### P <0.001 versus control; * P < 0.05, ** P < 0.01, *** P < 0.001 versus HHcy.