Research Paper Volume 10, Issue 11 pp 3294—3307

Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts

Figure 1. Targeting senescent cells with clinically-approved drugs. Here, we propose to use clinically-approved drugs, including antibiotics, to target and eliminate senescent cells, with the goal of increasing healthspan and lifespan.