Research Paper Volume 10, Issue 11 pp 3294—3307

Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts

Figure 3. Chemical structures of Erythromycin and related compounds. Note that Erythromycin, Azithromycin and Roxithromycin all have very similar chemical structures, but differ mainly in their side groups. All three compounds are macrolide antibiotics and consist of a large core macrocyclic lactone ring, with two deoxy-sugars attached to it.