Research Paper Volume 10, Issue 11 pp 3421—3437

miR-150-5p suppresses tumor progression by targeting VEGFA in colorectal cancer

Figure 8. miR-150-5p inhibited VEGFA/VEGFR2/Akt/mTOR signaling pathway in CRC. Western blot was used to measure the expression of VEGFA, VEGFR2, p-VEGFR2, Akt, p-Akt, mTOR, p-mTOR in transfected HCT116 and HCT8 cells. GAPDH was used as a loading control. Data are shown as the mean±SD of three independent experiments. *p<0.05, **p<0.01, ***p<0.001.