Figure 7. Genetic mutations in CBXs and their association with OS and DFS of HCC patients (cBioPortal). High mutation rate (51%) of CBXs was observed in HCC patients. CBX8, CBX1, CBX2 and CBX4 ranked the highest four genes of genetic alterations, and their mutation rates were 18%, 16%, 16% and 15%, respectively (A). Genetic alterations in CBXs were associated with shorter OS (B) and DFS (C) of HCC patients.