Figure 5. Premature senescence and elevated TGF-β1 in the murine CE with chronic failure. (A-C) Corneal graft phenotype in syngenic and chronic failure mouse model (D-E) p21, p16 (D) and TGF-β1 (E) expression was measured at transcription level in the murine CE from syngenic and chronic failure group. (F) Representative photographs for the IF staining of TGF-β1 in the CE with chronic graft failure. **P<0.01,*P<0.05.