Research Paper Volume 11, Issue 1 pp 18—32

MicroR-542-3p can mediate ILK and further inhibit cell proliferation, migration and invasion in osteosarcoma cells

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Figure 6. Low expression of ILK inhibited the proliferation of osteosarcoma cells. (A) The MTT assay revealed that overexpression of ILK (ILK group) promoted proliferation of osteosarcoma cells. **P<0.01 compared with the NC group; (B) Colony-forming growth assay was performed to determine the proliferation of pcDNA3.1-ILK group (ILK group), si-ILK group, pcDNA3.1-ILK+miR-542-3p mimics group (ILK+mimics group) and si-ILK+miR-542-3p inhibitor group (si-ILK+inhibitor group) transfected osteosarcoma cells. Colonies were counted and captured. **P<0.01 compared with the NC group.