Research Paper Volume 11, Issue 1 pp 18—32

MicroR-542-3p can mediate ILK and further inhibit cell proliferation, migration and invasion in osteosarcoma cells

Figure 6. Low expression of ILK inhibited the proliferation of osteosarcoma cells. (A) The MTT assay revealed that overexpression of ILK (ILK group) promoted proliferation of osteosarcoma cells. **P<0.01 compared with the NC group; (B) Colony-forming growth assay was performed to determine the proliferation of pcDNA3.1-ILK group (ILK group), si-ILK group, pcDNA3.1-ILK+miR-542-3p mimics group (ILK+mimics group) and si-ILK+miR-542-3p inhibitor group (si-ILK+inhibitor group) transfected osteosarcoma cells. Colonies were counted and captured. **P<0.01 compared with the NC group.