Research Paper Volume 11, Issue 1 pp 18—32

MicroR-542-3p can mediate ILK and further inhibit cell proliferation, migration and invasion in osteosarcoma cells

Figure 9. Effects of miR-542-3p overexpression on tumor growth in vivo. (A) Tumors were collected from nude mice injected with osteosarcoma cells transfected with miR-542-3p mimics or NC; (B) The tumor volume was analyzed every 5 days. **P<0.01 compared with the NC group; (C) The tumor weight was measured 30 days after tumor transplantation. **P<0.01 compared with the NC group; (D) Expression levels of ILK and miR-542-3p were measured by qRT-PCR in nude mice tissues. *P<0.05, **P<0.01 compared with the NC group; (E) Expression of ki67 and ILK in each group was detected by immunohistochemical staining.