Research Paper Volume 11, Issue 1 pp 63—72

Mesenchymal stem cells rejuvenate cardiac muscle after ischemic injury

Figure 5. Reduced cell apoptosis and ROS formation by CD146+MSCs against hypoxia in cardiac muscle cells. (A-D) The apoptosis of CMC in an Annexin V-apoptosis assay (A-B), shown by representative flow charts (A), and by quantification (B), and in a TUNEL assay (C-D), shown by quantification (C), and by representative images (D). (E) ROS levels by DCF-DA assay. *p<0.05. N=5. Scale bars are 50 µm.