Figure 2. The methylated-differentially expressed genes identification and function. (A) Venn of methylated-differentially expressed genes in gene expression datasets (GSE62232, GSE84402) and gene methylation datasets (GSE73003, GSE57956). (B) The volcano plot of GSE84402. Log2 (FC) vs. -log10 (p value) for differentially expressed mRNA. Red dot represents significant mRNA (log2|FC|>1, P<0.05). (C) The significant enriched gene ontology of MDEGs. (D) The significant enriched KEGG pathways of MDEGs.