Research Paper Volume 11, Issue 1 pp 160—173

A four-methylated mRNA signature-based risk score system predicts survival in patients with hepatocellular carcinoma

Figure 5. Construction of the Four MDEGs signature of HCC. The patients were stratified into high risk group and low risk group based on median of risk score. (A) Risk score distribution of HCC patients, Survival status of each patient and Expression heatmap of the four hub MDEGs corresponding to each sample above. Red: high expression; Blue: low expression. (B, C) The distribution of death (B) and disease-progression (C) in high and low risk group. (D, E) Kaplan-Meier estimates of the overall survival (D) and progression-free survival (E) time of patients using the four MDEGs signature based risk score. (F) The ROC curve of the four MDEGs signature.