Research Paper Volume 11, Issue 1 pp 240—248

Metformin prolongs lifespan through remodeling the energy distribution strategy in silkworm, Bombyx mori

Figure 1. Metformin increases the adult and total mean lifespan in the male silkworm. (A) Adult stage (n=27), (B) mean total lifespan (n=30), and (C) maximum lifespan (n=3) of unmated female silkworms administered metformin (Treatment) or deionized water (Control). (D) Adult stage (n=24), (E) mean total lifespan (n=54) and (F) maximum lifespan of unmated male silkworms administered metformin (Treatment) of deionized water (Control). Bars depict the mean + SEM, *P < 0.05, **P < 0.01, ***P < 0.001.