Research Paper Volume 11, Issue 2 pp 401—422

3,4,5-Tricaffeoylquinic acid induces adult neurogenesis and improves deficit of learning and memory in aging model senescence-accelerated prone 8 mice

Figure 1. Effect of ethanol extract of 3,4,5-triCaffeoylquinic acid (TCQA) on the spatial learning and memory as determined by escape latency of senescence-accelerated resistant mouse 1 (SAMR1) mice, senescence-accelerated prone mouse 8 (SAMP8) mice and SAMP8 TCQA-treated group determined by Morris water maze test (A). Effect of ethanol extract of TCQA on the time spent in the target quadrant (B). Effect of ethanol extract of TCQA on numbers of crossings of platform by SAMR1 untreated and SAMP8 treated or untreated mice (C). * P < 0.05, ** P < 0.01 Compared with SAMP8 + water group.