Research Paper Volume 11, Issue 2 pp 448—466

miRNA-mRNA crosstalk in myocardial ischemia induced by calcified aortic valve stenosis

Figure 4. Mitochondrial dysfunctions after myocardial ischemia in CAVS patients. (A) The chest CT of the CAVS patient. The yellow arrow refers to the calcified aortic valve; (B) The cardiac multifunctional color Doppler ultrasound image of the CAVS patient; (C) The electronic microscopy observation of mitochondria in CAVS myocardial tissues; (D) Confocal microscopy observation of mitochondrial morphology in H9C2 hypoxic simulated myocardial ischemia, bar=10μm. Quantitation is done in triplicate and scored into three categories: foreshortened, middle and elongated mitochondria. *P<0.05, **P<0.01.