Research Paper Volume 11, Issue 2 pp 615—633

MiR-223-3p promotes cell proliferation and metastasis by downregulating SLC4A4 in clear cell renal cell carcinoma


Figure 7. SLC4A4 overexpression attenuates the effects of miR-223-3p mimics on cellular processes. (A) MiR-223-3p and (B) SLC4A4 levels were measured by qRT-PCR in 786-O and Caki-1 cells. Overexpression of SLC4A4 impaired the effects of miR-223-3p mimics on (C) KRAS expression, (D) cell proliferation, (E) migration and (F) invasion in Caki-1 cells. Data are shown as the mean ± SEM. * p < 0.05; ** p < 0.01; *** p < 0.001.