<i>MALAT1</i>/miR-15b-5p/<i>MAPK1</i> mediates endothelial progenitor cells autophagy and affects coronary atherosclerotic heart disease via mTOR signaling pathway

Ying Zhu; Tianrui Yang; Jinlan Duan; Ninghui Mu; Tong Zhang

doi:doi:10.18632/aging.101766

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Research Paper Volume 11, Issue 4 pp 1089—1109

MALAT1/miR-15b-5p/MAPK1 mediates endothelial progenitor cells autophagy and affects coronary atherosclerotic heart disease via mTOR signaling pathway

Figure 10. En face analysis of thoracoabdominal aorta and cross-sections of the root of aorta. The atherosclerotic lesions throughout the aorta in ApoE−/− mice were lessened in the antagoMALAT1 group and the plaque area in ApoE−/− +HFD group was larger than that in ApoE−/− +RCD group. **P<0.01, compared with antagoNC group. ##P<0.01, compared with ApoE−/− + RCD group.