Research Paper Volume 11, Issue 3 pp 874—884

MAPT rs242557 variant is associated with hippocampus tau uptake on 18F-AV-1451 PET in non-demented elders

Figure 2. Quantitative comparisons for adjusted correlations of hippocampus tau PET SUVR levels with rs242557 variant in the subgroups categorized by Aβ pathology. (A) Left hippocampus tau PET SUVR for each subject in the Aβ-positive group is plotted separated by rs242557 genotype (adjusted β = 0.206, p = 0.001, Bonferroni corrected p = 0.029). (B) Right hippocampus tau PET SUVR for each subject in the Aβ-positive group is plotted separated by rs242557 genotype (adjusted β = 0.198, p = 0.001, Bonferroni corrected p = 0.035). (C) Left hippocampus tau PET SUVR for each subject in the Aβ-negative group is plotted separated by rs242557 genotype (adjusted β = 0.083, p = 0.035, Bonferroni corrected p = 0.878). (D) Right hippocampus tau PET SUVR for each subject in the Aβ-negative group is plotted separated by rs242557 genotype (adjusted β = 0.075, p = 0.037, Bonferroni corrected p = 0.930).