Figure 5. MiR-141 inhibits HNSCC metastasis. (A-D) Transwell assays with and without Matrigel showing the effect of miR-141 on FaDu and Cal-27 cell migration and invasion. Left panels: representative images of migrated cells under the indicated conditions. Right panels: Group data showing counts of migrated cells. Bars depict the mean ± SD of three experiments. (E-H) Western blots and real-time PCR the effect of miR-141 mimic and inhibitor on MMP2 expression in FaDu and Cal-27 cells. Bars depict the mean ± SD. ** P< 0.05 vs. control.