Research Paper Volume 11, Issue 4 pp 1177—1188

Nutraceutical effects of Emblica officinalis in age-related macular degeneration

Figure 7. Effect of EO on VEGF gene expression and on cell viability and ROS levels in amyloid-β-stressed AMD cells. This figure showed down-regulation of VEGF gene in EO-treated AMD cybrids (A). Pretreatment with EO rescued AMD cybrids from amyloid-β-induced damage as shown by changes in cell viability (B (bar 2 versus bar 5) and ROS levels (C (bar 2 versus bar 5). *, **, and *** indicate p<0.05, p<0.01, and p<0.001 respectively; ns indicates non-significant p-value. Data are presented as mean ± SEM and normalized to untreated AMD cybrids which were assigned a value of 1.