Research Paper Volume 11, Issue 4 pp 1189—1203

Age and poverty status alter the coding and noncoding transcriptome

Figure 1. Changes in lncRNA abundance with age and poverty. The lncRNA expression levels in white young and old males (A) living above or below poverty (B) were assessed using microarrays (Table 1 for demographic details). Volcano plots show log2 fold change and P value for each lncRNA. Red indicates lncRNAs that were >2-fold change and P<0.05. (A,B,D) lncRNA comparisons between groups are indicated. (C) Heat maps indicate the top fold changed lncRNAs with age and poverty. These lncRNAs are also listed in Tables 2 and 3. (E) Venn diagram of the total number of significantly increased or decreased lncRNAs for each comparison. Y, young; O, old, AP, above poverty; BP, below poverty.