Research Paper Volume 11, Issue 4 pp 1189—1203

Age and poverty status alter the coding and noncoding transcriptome

Figure 3. Validation of age and poverty associated level changes in lncRNAs abundance. (A) lncRNAs significantly changed in abundance with age and poverty in white males were compared to lncRNAs identified in the literature to be age-associated. Overlapping lncRNAs are shown. (B-C) RNA was isolated from PBMCs from young (mean=32.1 yrs) and old (mean=62.6 yrs) white males above and below poverty (n=40; see Table 1 for demographics). RNA was reverse transcribed and lncRNA levels were quantified by RT-qPCR.