Research Paper Volume 11, Issue 4 pp 1204—1225

m6A RNA methylation regulators contribute to malignant progression and have clinical prognostic impact in gliomas

Figure 4. Risk signature with seven m6A RNA methylation regulators. (A) The process of building the signature containing seven m6A RNA methylation regulators. The hazard ratios (HR), 95% confidence intervals (CI) calculated by univariate Cox regression and the coefficients calculated by multivariate Cox regression using LASSO are shown. (B–C) Kaplan–Meier overall survival (OS) curves for patients in the CGGA (B) and TCGA (C) datasets assigned to high- and low-risk groups based on the risk score.