Research Paper Volume 11, Issue 4 pp 1226—1239

Methane alleviates sepsis-induced injury by inhibiting pyroptosis and apoptosis: in vivo and in vitro experiments

Figure 1. Methane-rich saline improved the survival ratio of mice. Kaplan-Meier survival curve for mice 5 days after the cecal ligation and puncture (CLP) operation (n = 9). Sham control group received 2.5ml/kg normal saline every 12 h; Normal saline (NS) group received 2.5ml/kg normal saline every 12 h; Methane-rich saline (MRS) group (5ml/kg) received 5mL/kg MRS every 12 h; MRS group (10ml/kg) received 10mL/kg MRS every 12 h; MRS group (20ml/kg) received 20mL/kg MRS every 12 h.