Research Paper Volume 11, Issue 5 pp 1486—1500

Integrated DNA methylation and gene expression analysis in the pathogenesis of coronary artery disease

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Figure 2. The PCA and volcanoplot for DMPs. (A) For the PCA map, the red strip represents the healthy control and the blue strip atherosclerosis samples. (B) For the valcano plot, the two vertical lines are the 0.05-fold change boundaries and the horizontal line is the statistical significance boundary (P < 0.05). Items with statistical significance and hypermethylation are marked with red dots and hypomethylation are marked with blue dots in the volcano plot.