Research Paper Volume 11, Issue 5 pp 1486—1500

Integrated DNA methylation and gene expression analysis in the pathogenesis of coronary artery disease

Figure 5. PPI network construction and identification of hub items. (A) PPI network of the selected DMaGs. The edge shows the interaction between two genes. Significant modules identified from the PPI network using the molecular complex detection method with a score > 6.0. (B) Molecular-1 with MCODE = 11; (C) Molecular-2 with MCODE = 8. A degree was used to describe the importance of protein nodes in the network, with a dark color filling denoting a high degree and light color a low degree.