Research Paper Volume 11, Issue 5 pp 1501—1509

Curcumin inhibits liver metastasis of gastric cancer through reducing circulating tumor cells

Figure 3. Curcumin reduces CTCs of s.c. grafted PGCs. (A) Schematic: The PGCs were subcutaneously grafted into NOD/SCID mice to generate xenografted tumor, after which some mice received liposomal Curcumin while some received liposome as controls. The presence of CTCs in the circulation was assessed by flow cytometry for GFP at 3, 6, 9 weeks after transplantation, 12 weeks after transplantation in mice with or without Curcumin treatment. (B) Representative flow charts for a negative detection or a positive detection of CTCs by flow cytometry. (C) Ratio of detection of CTCs. *p<0.05. N=30.