Research Paper Volume 11, Issue 5 pp 1564—1579

Running wheel access fails to resolve impaired sustainable health in mice feeding a high fat sucrose diet

Figure 6. Glucose and cholesterol blood plasma results. (A) Blood glucose after 6 hours of fasting; (B) Blood insulin after 6 hours of fasting, increased with age and eating a HFS diet and decreased with having access to a running wheel; (C) HOMA-IR index was improved in mice on a LF diet; (D) Total plasma cholesterol was higher in mice on a HFS diet; (E) free plasma cholesterol was highest in mice on a HFS diet in combination with access to a running wheel (F) plasma cholesteryl esters was higher in mice on a HFS diet. Data are averages from n=6-8 mice per group; + SEM. *p<0.05, **p<0.01, ***p<0.001 (per time point analysis (Bonferonni corrected)).