Research Paper Volume 11, Issue 6 pp 1778—1790

Anesthesia and surgery induce cognitive dysfunction in elderly male mice: the role of gut microbiota

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Figure 6. ROC curves of the gut bacterium count for the diagnosis of anesthesia- and surgery-induced POCD. (A) Phylum Chlamydiae (AUC, 0.837). (B) Phylum Tenericutes (AUC, 0.755). (C) Phylum TM7 (AUC, 0.612). (D) Class Betaproteobacteria (AUC, 0.857). (E) Class Chlamydiae (AUC, 0.837). (F) Class Erysipelotrichia (AUC, 0.857). (G) Class Mollicutes (AUC, 0.755). (H) Class TM7-3 (AUC, 0.612). (I) Order Anaeroplasmatales (AUC, 0.816). (J) Order Burkholderiales (AUC, 0.857). (K) Order Chlamydiales (AUC, 0.837). (L) Order CW040 (AUC, 0.612). (M) Order Erysipelotrichales (AUC, 0.857). (N) Family Alcaligenaceae (AUC, 0.857). (O) Family Anaeroplasmataceae (AUC, 0.816). (P) Family Chlamydiaceae (AUC, 0.837). (Q) Family Dehalobacteriaceae (AUC, 1.0). (R) Family Erysipelotrichaceae (AUC, 0.857). (S) Family-F16 (AUC, 0.612). (T) Genus Anaeroplasma (AUC, 0.816). (U) Genus Chlamydia (AUC, 0.837). (V) Genus Dehalobacterium (AUC, 1.0). (W) Genus Sutterella (AUC, 0.857). (X) Species Escherichia coli (AUC, 0.857). A + S: anesthesia and surgery; AUC: area under curve; ROC: receiver operating characteristic.